diff --git a/lib/internal/blob.js b/lib/internal/blob.js
index 68071a5f5645e7..e85438f5d5704b 100644
--- a/lib/internal/blob.js
+++ b/lib/internal/blob.js
@@ -475,9 +475,13 @@ function createBlobReaderStream(reader) {
       this.pendingPulls = [];
       // Lazily register a wakeup callback that the C++ side can invoke
       // when new data is available after a STATUS_BLOCK.
+      let immediate;
       this.wakeup = () => {
         if (this.pendingPulls.length > 0) {
-          this.readNext(c);
+          immediate ??= setImmediate(() => {
+            immediate = undefined;
+            this.readNext(c);
+          });
         }
       };
     },
@@ -577,7 +581,15 @@ const kMaxBatchChunks = 16;
 async function* createBlobReaderIterable(reader, options = kEmptyObject) {
   const { getReadError } = options;
   let wakeup = PromiseWithResolvers();
-  reader.setWakeup(wakeup.resolve);
+  let immediate;
+  let fin = false;
+  reader.setWakeup((setfin) => {
+    fin ||= setfin;
+    immediate ??= setImmediate(() => {
+      immediate = undefined;
+      wakeup.resolve?.();
+    });
+  });
 
   try {
     while (true) {
@@ -622,9 +634,8 @@ async function* createBlobReaderIterable(reader, options = kEmptyObject) {
       if (error) throw error;
 
       if (blocked) {
-        const fin = await wakeup.promise;
+        await wakeup.promise;
         wakeup = PromiseWithResolvers();
-        reader.setWakeup(wakeup.resolve);
         // If the wakeup was triggered by FIN (EndReadable), the DataQueue
         // is capped. Continue the loop to pull again -- the next pull will
         // return EOS. Without this, a race between the data notification